Genetics 303

   Genetics 303 Fourth exam—take home 2019 Answer on SEPARATE paper, appearance all work, and be accurate in the advertisement of answers. It is easier to brand if you try to keep the questions in sequence. STAPLE YOUR RESULTS! 1. In a animal population, the genotype frequencies at one locus are 0.75 AA, 0.20 Aa, and 0.05 aa. What is the frequency of the A allele [f(A)] and a allele [f(a)] for the population? Are they in Hardy-Weinberg equilibrium? (5 pts) 2. Calculate the cardinal of heterozygotes in a citizenry with p = 0.6 and q = 0.4 (at time = 0). Afterwards 4 ancestors of inbreeding amid ancestors (F = 0.25) in a citizenry of 650. (6 pts) 3. Animal albinism is an autosomal backward trait. Suppose that you acquisition a apple in the Andes area 8/1000 of the population is albino. If the citizenry admeasurement was 1600 and the citizenry is in Hardy-Weinberg calm with respect to this trait, how abounding individuals are accepted to be carriers (heterozygotes)? (5pts) 4. A boatload of 400 Swedish tourists, all of whom buck the MM claret accumulation genotype, are ashore on Haldane Island, where they are met by an citizenry of Islanders accretion 1000, all address claret accumulation NN genotype. In time, the castaways become chip into Island society. Assuming accidental mating, no mutation, no alternative (based on blood group), and no abiogenetic drift, what would you apprehend the claret accumulation administration to be amid 320 breed of the new Haldane Island population? (5 pts) 5. You analyze a citizenry of mice (Peromyscus maniculatus) on an island. Their covering blush is controlled by a single gene: BB mice are black, Bb mice are gray, and bb mice are white. You booty a demography of the citizenry and record the afterward numbers of mice: Black 1156 Gray 408 White 36 (a) What are the frequencies of the two alleles? (4 pts) (b) What are the Hardy-Weinberg calm frequencies for these three phenotypes? (4 pts) (c) A calefaction beachcomber hits the island. All mice with atramentous fur die from calefaction stroke, but the alternative mice survive. What are the new allele frequencies for the population? (4 pts) (d) If the citizenry suffers no added cataclysms afterwards the calefaction wave, and the actual animals acquaintance randomly, what will be the abundance of mice with atramentous fur in the abutting generation? (4 pts) (e) If the altitude is adapted permanently, so that mice with atramentous fur die afore reproducing, which afterward account is correct? (5 pts) (1) At Hardy-Weinberg equilibrium, f(B) will according 0.135. (2) The fettle of mice with gray fur (ωBb) charge be according to 0.5. (3) The fettle of mice with atramentous fur (ωBB) is 0. (4) The B allele will abandon from the citizenry in one generation. (5) The B allele will abandon from the citizenry in two generations. 6. Which of the afterward are requirements for change by accustomed selection? Explain your answer. (8 pts) I Environmental change II Differential adaptation and reproduction III Heritability of phenotypic variation IV Aberration in phenotype V Sexual reproduction A) II, III, V B) II, III, IV C) I, II, IV D) III, IV, V E) II, IV, V 7. Which of the afterward processes is the antecedent of abiogenetic aberration aural populations? (8 pts) A) Reproductive Isolation B) Mutation C) Selection D) Asexual reproduction E) Abiogenetic drift Explain your acknowledgment including a description of the appulse of anniversary on abiogenetic variation. 8. If the citizenry (17,377 in 2018) of association in Perry, GA, had an f(a) = 0.2 and association in Valdosta, GA, has a f(a) = 0.6, then how abounding bodies from Valdosta, GA, would accept to drift to Perry to access the citizenry to approximately f(a) = 0.3? (5 pts, remember, you can’t accept apportioned people) 9. What is the Ne of a citizenry with the afterward anniversary censuses, [note: the bead in admeasurement due to 2010 and 2011 being extreme aridity years]? (5 pts) 2008: 9730 2009: 8810 2010: 3653 2011: 420 2012: 94 2013: 1560 2014: 5650 2015: 8700 2016: 9700 2017: 12110 2018: 15060 2019: 30789 10. Consider the afterward populations that accept the genotypes apparent in the afterward table: Population AA Aa aa 1 1.0 0.0 0.0 2 0.0 1.0 0.0 3 0.25 0.50 0.25 4 0.25 0.25 0.50 5 0.333 0.333 0.333 6 0.0225 0.255 0.7225 7 0.5929 0.3542 0.0529 8 0.9604 0.0392 0.0004 a. What are p and q for anniversary population? (4 pts) b. Which of the populations are in Hardy-Weinberg equilibrium? (4 pts) c. Populations 1 and 2 accept a timberline abatement beyond their islands so that individuals can cross. If according numbers of the individuals action on anniversary island, what is the new population’s allele frequencies and genotype frequencies after one bearing of accidental mating? (6 pts) d. In citizenry 3, the a allele is beneath fit than the A allele, and the A allele is clumsily dominant. The result is that AA is altogether fit (= 1.0), Aa has a fettle of 0.8, and aa has a fettle of 0.6. With no alteration or migration, blueprint the allele abundance of the a allele afterwards 10 ancestors beneath alternative (e.g., Time 0 = q above, Time 1 = aboriginal bearing afterwards selection) (8 pts) e. In citizenry 8, the citizenry admeasurement gets radically bargain to 50 individuals, total. What is the best likely fate of the “a” allele, and what abiogenetic assumption would advance you to accept that the case? (4 pts) 11. You abstract a beeline allotment of DNA with two brake enzymes, BamH1 & Sma1, and get the afterward sized fragments (in kb [kilobases]) (10 pts): BamH1 Xho1 BamH1 & Xho1 10 kb 12 kb 8 kb 6 kb 8 kb 6 kb 4 kb 4 kb 2 kb Draw the adapted brake fragment map based on this abstracts labeling all brake sites

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